Hematology Coulter cell counters are laboratory instruments used to count and analyze blood cells. They are based on the principle of electrical impedance and light scattering , where cells passing through a narrow orifice generate an electrical pulse that is proportional to their size and volume. There are several types of hematology Coulter cell counters available on the market, each with its own unique features and capabilities. Here are some of the most common types:
- 3-Part Differential Hematology Analyzers: These analyzers are designed for routine blood analysis and can measure the complete blood count (CBC), including the number and types of white blood cells, red blood cells, and platelets. They are usually automated and can process large volumes of samples in a short amount of time. useful in small budget and low volume workload lab .You will need to review peripheral smear for absolute counts.
- 5-Part Differential Hematology Analyzers: These analyzers are more advanced than 3-part analyzers and can distinguish between different types of white blood cells, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. useful in screening and diagnosing leukemia. Provide absolute eosinophil and Basophil count.Newer versions now provide reticulocyte count (using RNA fluorescent dyes or supravital specific dyes with laser light to test reticulocyte and related parameters) and immature platelet fraction(IPF) The IPF is an early indicator of platelet production and typically elevated in disorders of platelet destruction, such as ITP, TTP, and DIC.
- 6 -part Differential Hematology Analyzers: . They are able to classify immature granlulocytes (IG) as a sixth population and report them as a percentage count of the total WBC count as an absolute count which help in screening for blasts.
- Point-of-Care Hematology Analyzers: These analyzers are portable and can be used at the point of care, such as in clinics or hospitals. These instruments only provide Hemoglobin.
There are several high-quality Coulter counters available on the market, each with its own unique features and capabilities. Here are some of the best Coulter counters available:
Beckman Coulter DXH800,DXH500
Sysmex XN330, XN1000
Horiba ABX series,YumizenH550
Abbot alinity H series
Ultimately, the best Coulter counter for you will depend on your specific needs and budget. It is best to consult with a scientific equipment vendor or a laboratory specialist to determine which Coulter counter will be best suited for your needs.
Disclaimer:we are not endorsing any of the above product