Mantoux test -procedure

What is the Mantoux test? The Mantoux test, also known as the tuberculin skin test, is a test used to screen for tuberculosis (TB) infection. It is not used to diagnose active TB disease. The test is performed by injecting a small amount of tuberculin purified protein derivative (PPD) into the skin of the forearm. … Read more

AMH (Anti-Mullerian Hormone)-AMH Lab Testing

Antimullerian hormone (AMH), is a dimeric glycoprotein, a member of the transforming growth factor beta superfamily which acts on tissue growth and differentiation AMH is produced by Sertoli cells of the testis in males and by ovarian granulosa cells in females. In women AMH levels represent the ovarian follicular pool and could be a useful … Read more

What is the Sulfosalicylic Acid Test for Proteinuria?

Sulfosalicylic acid test (SSA) is a semiquantitative simple and inexpensive test for detection of protein in urine . It is not as sensitive as other tests for proteinuria, such as the urine dipstick test, but it is more specific. This means that it is less likely to give a false positive result. Presence of abnormal … Read more

Reticulocyte count – procedure, corrected reticulocyte count

Introduction : A reticulocyte count is a laboratory test that measures the number of immature red blood cells, known as reticulocytes, in the bloodstream. New methylene blue or brilliant cresyl blue (supravital stains) allow visualization of the reticulin network of erythrocyte  ribosome in  newly formed red blood cells Why Is Reticulocyte Count Important? Reticulocyte is … Read more

Tumor Markers: A Comprehensive Guide for Students

Introduction: Tumor markers are substances produced by both healthy and cancerous cells in the body. They play a crucial role in the diagnosis, monitoring, and management of various types of cancers. Having a strong understanding of tumor markers is essential to contribute effectively to cancer diagnostics and patient care. In this article, we will explore … Read more

HPLC-Definition, principle uses in clinical diagnostics

High-performance liquid chromatography (HPLC) is a powerful analytical technique used to separate and identify compounds in a liquid mixture. It is a versatile technique that can be used in a wide variety of applications, including the pharmaceutical industry, environmental analysis, and clinical diagnostics. Principle of HPLC The basic principle of HPLC is the partitioning of … Read more

Order of blood Draw-CLSI guidelines

ORDER OF BLOOD DRAW IN PHLEBOTOMY-CLSI GUIDELINES

The Order of Blood Draw in Phlebotomy Order of blood draw in multiple tube collection CLSI guidelines The Clinical and Laboratory Standards Institute (CLSI) has a guideline on the order of blood draw. The guideline is called GP41: Collection of Diagnostic Venous Blood Specimens. The guideline recommends the following order of draw: Phlebotomy is the … Read more

PTH intact hormone test

PTH intact test, also known as parathyroid hormone (PTH) 1-84 test, is a blood test that measures the level of parathyroid hormone (PTH) in the blood. PTH is a hormone that is produced by the parathyroid glands, which are four small glands that are located in the neck, near the thyroid gland. PTH helps to … Read more

Cyfra 21-1 test

What is the Cyfra 21-1 test? The Cyfra 21-1 is a blood test to measure levels of Cyfra 21-1. CYFRA 21-1 is a tumor marker that is used to help diagnose and monitor lung cancer, especially non-small cell lung cancer (NSCLC). Cyfra 21-1 is a fragment of cytokeratin 19, a protein that is found in … Read more

FDA Clears Roche’s CSF Biomarkers for Alzheimer’s Disease

biomarker for alzheimers disease

Roche has obtained FDA clearance for Alzheimer’s tests in the U.S. that include two ratios comprising three assays. The Elecsys® beta-Amyloid (1-42)(Abeta42) protein , Elecsys® Phospho-Tau (181P) CSF , total-Tau CSF (tTau)can aid in the diagnosis of Alzheimer’s disease by measuring levels of beta-amyloid and tau protein. The Abeta42 and pTau181 assays are currently available, while the total … Read more